11-cs01-data

Professor Shannon Ellis

2/14/23

CS01: Biomarkers of Recent Use (Data)

Q&A

Course Announcements

Agenda

  • Background
  • Data Intro
  • Wrangle
  • Combine!

Background

Motor Vehicle Accidents (MVAs)

  • 2/3 of US trauma center admissions are due to MVAs
  • ~60% of such patients testing positive for drugs or alcohol
  • Alcohol and cannabis are most frequently detected

Source: https://academic.oup.com/clinchem/article/59/3/478/5621997

Legalization of Marijuana

  • Federally illegal in the US
  • Decriminalized in many states
  • Medically available in
  • Legal for recreational use in …

Increased roadside surveys

  • 25% increase in use nationwide from 2002 to 2015 (survey)
  • THC detection in drivers increased by 48% from 2007 to 2014
  • Increased prevalence of consumption -> possible intoxication -> possible impaired driving -> public health concern

DUI of Alcohol (DUIA)

  • The science is there. Don’t do it.
  • DUIA has decreased since the 1970s
    • % of nighttime, weekend drivers testing over the legal limit (BAC > 0.08 g/dL) decreased from 7.5% (1973) to 2.2% (2007)

DUI of Cannabis

  • In a 2007 survey1, 16.3% of nighttime drivers were drug-positive
    • 8.6% of these tested positive for THC
  • Experimental and cognitive studies suggest cannabis-induced impairment increases risk of motor vehicle crashes:

Evidence suggests recent smoking and/or blood THC concentrations 2–5 ng/mL are associated with substantial driving impairment, particularly in occasional smokers.2

per se limits

Questions

The Data

Experimental Design

Wrangling

https://cogs137.github.io/website/